This Article  • References  • Full text PDF  • Send to a friend  • Save in My Folder  • Save to citation manager  • Permissions  Citing Articles  • Citing articles on Web of Science (8)  • Contact me when this article is cited  Related Content  • Similar articles in this journal  Social Bookmarking   What's this?

Steven T. Ruby, MD; Medhat E. Allam, MD; MaryAnn Gallo; Sara Barth; Salwa A. Elgebaly, PhD

Arch Surg. 1990;125(4):481-484.

Abstract
• With the use of arterial bypass release neutrophil chemotactic factors, saphenous veins were removed from dogs by means of standard surgical technique and were distended to a pressure of 200 mm Hg for 15 minutes with cold (4°C) plasmalyte solution. Veins cannulated in situ and flushed with cold (4°C) plasmalyte solution served as negative controls. Experimental and control flush solutions were assayed for the presence of neutrophil chemotactic factors with the use of modified Boyden chambers. Chemotactic activity from the distended vein grafts was 2.2 to 7.2 times the control value. Biologic chemotactic activity was demonstrated as well. These results suggest a role for the vein graft itself in the recruitment of neutrophils to implanted veins by releasing chemoattractants.

(Arch Surg. 1990;125:481-484)

Author Affiliations
From the Surgical Research Center, Department of Surgery, University of Connecticut Health Center, Farmington, and Newington (Conn) Veterans Hospital.

Footnotes
Accepted for publication November 13, 1989.

Read before the 13th Annual Meeting of the Association of Veterans Administration Surgeons, San Antonio, Tex, May 5, 1989.

Reprint requests to Surgical Research Center, Department of Surgery, University of Connecticut Health Center, Farmington, CT 06032 (Dr Ruby).

CiteULike    Connotea    Del.icio.us    Digg    Reddit    Technorati    Twitter     What's this?