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Carolyn M. Kaelin, MD; Michael J. Im, PhD; Roy A. M. Myers, MD; Paul N. Manson, MD; John E. Hoopes, MD

Arch Surg. 1990;125(5):607-609.

Abstract
• The effects of hyperbaric oxygen on survival were investigated in free flaps and island flaps. Skin flaps transplanted following 18,21, and 24 hours of preservation at 24°C demonstrated survival rates of 20%, 10%, and 0%, respectively. Treatment with hyperbaric 100% oxygen improved the survival rates to 66%, 67%, and 40%. A preservation time of 21 to 24 hours at room temperature appears to be the threshold of irreversible ischemic damage. In acute island flaps, flap survival was improved significantly from 35% to 53% and 64% of the random flap area by preoperative or postoperative treatment, respectively. Prolonged preoperative and postoperative treatment improved survival to 66%.

(Arch Surg. 1990;125:607-609)

Author Affiliations
From the Division of Plastic Surgery, The Johns Hopkins University School of Medicine (Drs Kaelin, Im, and Hoopes), and the Section of Hyperbaric Medicine, Maryland Institute for Emergency Medical Services Systems (Drs Myers and Manson), Baltimore. Dr Kaelin is now at the New England Medical Center, Boston, Mass.

Footnotes
Accepted for publication June 17, 1989.

Reprint requests to Department of Hyperbaric Medicine, Maryland Institute for Emergency Medical Services Systems, 22 S Greene St, Baltimore, MD 21201 (Dr Myers).

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