The neodymium-YAG laser and gastrointestinal malignancy
M. L. Eckhauser
Department of Surgery, Metro Health Medical Center, Case Western Reserve University, Cleveland, Ohio.
Thirty-seven patients with either bleeding or obstructive metastatic
gastrointestinal malignant neoplasms were treated with the neodymium-YAG
laser between June 1985 and December 1988. The age range for the group was
55 to 99 years, with a mean of 71 years. There were 25 upper
gastrointestinal lesions, including 22 obstructive lesions (20 esophageal
and two prepyloric gastric) and three bleeding lesions (one metastatic
melanoma to the stomach, one duodenal, and one pancreatic carcinoma). Of
the esophageal tumors, three were proximal, eight were middle, and nine
were distal third. The mean number of laser treatments was 2.6, and the
overall survival ranged from 1 to 20 months, with a median of 8 months. The
dysphagia grade was improved overall but depended on the site of the tumor.
All bleeding lesions were successfully photocoagulated. Twelve colorectal
malignant neoplasms were treated palliatively, six for obstruction (three
intraperitoneal colon and three rectal) and six for bleeding (three
intraperitoneal and three rectal). The mean number of treatments for the
group was 1.5, and the overall survival ranged from 2 to 38 months, with a
median survival of 15 months. The neodymium-YAG laser was found to be
effective as a palliative mode of therapy for the management of malignant
gastrointestinal lesions.