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Lower Extremity Arterial Disease in Systemic Lupus Erythematosus
Micheal J. Wheatley, MD;
Hani A. Hennein, MD;
Lazar J. Greenfield, MD
Arch Surg. 1991;126(1):109-110.
Abstract
Lupus vasculitis primarily affects microvascular circulation, and large-vessel thrombosis is a rare complication of this disease. Large-vessel occlusive disease in systemic lupus erythe-matosus is most likely related to hypercoagulability in addition to immune complex–mediated endothelial damage. We describe the 11th and 12th patients reported to have systemic lupus erythematosus and macrovascular occlusive disease of the lower extremities. Our experience and a review of the literature suggest that, while aortoiliac disease is amenable to bypass or endarterectomy, infrainguinal disease is rarely correctable surgically, and amputation becomes necessary in most of these patients.
(Arch Surg. 1991;126:109-110)
Author Affiliations
From the Department of Surgery, Section of Vascular Surgery, University of Michigan Medical School, Ann Arbor.
Footnotes
Accepted for publication July 22, 1990.
Reprint requests to Department of Surgery, University of Michigan Medical Center, 1500 E Medical Center Dr, Ann Arbor, MI 48109 (Dr Greenfield).
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ABSTRACT
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