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A 10-Year Experience

William K. Becker, MD; William G. Cioffi, Jr, MD; Albert T. McManus, PhD; Seung H. Kim, MD; William F. McManus, MD; Arthur D. Mason, MD; Basil A. Pruitt, Jr, MD

Arch Surg. 1991;126(1):44-48.

Abstract
• To evaluate our experience with fungal burn wound infection, we performed a 10-year review for comparison with our experience with bacterial burn wound infection. During the study period, a marked decline occurred in bacterial wound infection but not in fungal wound infection. Patients with either bacterial or fungal burn wound infection had massive injury, with burn size averaging greater than 50% of the total body surface area. Factors that appear to have markedly reduced bacterial burn wound infection, including patient isolation, topical chemotherapeutic agents, and burn wound excision, do not appear to have had a similar effect on fungal wound infection. The mechanism of spread and colonization of fungi, and the lack of effective topical chemotherapeutic antifungal agents, may explain in part our findings.

(Arch Surg. 1991;126:44-48)

Author Affiliations
From the US Army Institute of Surgical Research, Fort Sam Houston, San Antonio, Tex.

Footnotes
Accepted for publication September 29, 1990.

Read before the Tenth Anniversary Meeting of the Surgical Infection Society, Cincinnati, Ohio, June 14, 1990.

The opinions are those of the authors and do not purport to represent the views of the Department of the Army or the Department of Defense.

Reprint requests to the US Army Institute of Surgical Research, Fort Sam Houston, San Antonio, TX 78234-5012 (Dr Becker).

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