You are seeing this message because your Web browser does not support basic Web standards. Find out more about why this message is appearing and what you can do to make your experience on this site better.


ABOUT ARCHIVES
Advanced Search

Welcome   | My Account | E-mail Alerts | Access Rights | Sign In


  Vol. 126 No. 11, November 1991 TABLE OF CONTENTS
  Archives
  •  Online Features
  ARTICLE
 This Article
 •Send to a friend
 • Save in My Folder
 •Save to citation manager
 •Permissions
 Citing Articles
 •Citation map
 •Citing articles on HighWire
 •Contact me when this article is cited
 Related Content
 •Similar articles in this journal

Total axillary lymphadenectomy in the management of breast cancer

G. M. Senofsky, F. L. Moffat Jr, K. Davis, M. M. Masri, K. C. Clark, D. S. Robinson, B. Sabates and A. S. Ketcham
Department of Surgery, University of Miami School of Medicine, FL 33101.

The optimal extent of axillary dissection in patients with breast cancer remains unclear. We report 278 total axillary lymphadenectomies (levels I, II, and III and Rotter's [interpectoral] nodes) that were performed in 264 closely followed up private patients. There have been no axillary recurrences to date (mean follow-up, 50 months). If only level I and II nodes had been removed, the false-negative staging error would have been only 2.6%. However, 29 (31.5%) of 92 pathological node-positive axillae contained apical and/or Rotter's metastases. The incidence of complications was comparable with that reported for partial lymphadenectomy. Arm lymphedema developed in 6% of nonirradiated patients; postoperative radiotherapy and gross nodal disease were significant risk factors for lymphedema. Total axillary lymphadenectomy largely prevents axillary, recurrence, eliminates the small staging error inherent in partial lymphadenectomy, and has acceptable morbidity, provided radiotherapy to the regional nodal areas is avoided.

THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES

Breast Cancer: In Vivo Proton MR Spectroscopy in the Characterization of Histopathologic Subtypes and Preliminary Observations in Axillary Node Metastases
Yeung et al.
Radiology 2002;225:190-197.
ABSTRACT | FULL TEXT  

Radioguided Sentinel Lymph Node Biopsy in Breast Cancer Surgery
Mariani et al.
JNM 2001;42:1198-1215.
ABSTRACT | FULL TEXT  

Development and Validation of a Telephone Questionnaire to Characterize Lymphedema in Women Treated for Breast Cancer
Norman et al.
ptjournal 2001;81:1192-1205.
ABSTRACT | FULL TEXT  

Arm Edema in Breast Cancer Patients
Erickson et al.
JNCI J Natl Cancer Inst 2001;93:96-111.
ABSTRACT | FULL TEXT  

Axillary staging of breast cancer and the sentinel node
Cserni
J. Clin. Pathol. 2000;53:733-741.
ABSTRACT | FULL TEXT  

Prospective Observational Study of Sentinel Lymphadenectomy Without Further Axillary Dissection in Patients With Sentinel Node-Negative Breast Cancer
Giuliano et al.
JCO 2000;18:2553-2559.
ABSTRACT | FULL TEXT  





HOME | CURRENT ISSUE | PAST ISSUES | TOPIC COLLECTIONS | CME | SUBMIT | SUBSCRIBE | HELP
CONDITIONS OF USE | PRIVACY POLICY | CONTACT US | SITE MAP
 
© 1991 American Medical Association. All Rights Reserved.