Patterns of recurrence after pelvic exenteration for colorectal adenocarcinoma
G. H. Hafner, L. Herrera and N. J. Petrelli
Department of Surgical Oncology and Endoscopy, Roswell Park Cancer Institute, Buffalo, NY 14263.
We performed a retrospective review of 68 patients who underwent pelvic
exenteration for colorectal adenocarcinoma. Forty-seven patients had
surgery for primary disease and 21 for recurrence. Clinical recurrence
developed in 30 (44%) of 68 patients overall. Of these, 17 (57%) developed
locoregional disease only as their first recurrence. This included nine
(56%) of 16 patients with primary disease and eight (57%) of 14 patients
with recurrent disease. Clinical recurrence developed in 16 (34%) of 47
patients with primary disease and 14 (66%) of 21 patients with recurrent
disease. The overall 5-year survival rates were 43% and 20%, respectively.
We conclude that locoregional recurrence remains a significant problem for
primary or recurrent colorectal carcinoma even after radical pelvic
surgery.
