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  Vol. 126 No. 4, April 1991 TABLE OF CONTENTS
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  PAPERS READ BEFORE THE 43RD ANNUAL CANCER SYMPOSIUM OF THE SOCIETY OF SURGICAL ONCOLOGY, WASHINGTON, DC, MAY 19 TO 22, 1990-PAR T II
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Narrow Excision (1-cm Margin)

A Safe Procedure for Thin Cutaneous Melanoma

Umberto Veronesi; Natale Cascinelli, MD

Arch Surg. 1991;126(4):438-441.


Abstract



• We analyzed the results at 8 years of an international, randomized, prospective study carried out by the World Health Organization Melanoma Programme aimed at evaluating the efficacy of 1-cm-margin excision of primary melanomas not thicker than 2 mm. Data for 612 patients were assessable; 305 were randomized to receive 1-cm-margin excision and 307 to receive wide excision (margins of ≤3 cm). The major prognostic criteria were similar in the two groups. Breslow thickness was 0.99 mm in the narrow excision group and 1.02 mm in the wide excision group. Disease-free and overall survival rates (mean follow-up period, 90 months) were similar in the two groups. Only four patients had a local recurrence as a first relapse. All underwent narrow excision, and each had primary melanomas thicker than 1 mm.

(Arch Surg. 1991;126:438-441)



Author Affiliations



From the World Health Organization Melanoma Programme, National Tumor Institute, Milan, Italy.


Footnotes



Accepted for publication November 23, 1990.

Read before the 43rd Annual Cancer Symposium of the Society of Surgical Oncology, Washington, DC, May 20, 1990.

Reprint requests to Division of Surgical Oncology "B," Istituto Nazionale Tumori, Via Venezian, 1, 20133 Milano, Italy (Dr Cascinelli).



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