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A Pilot Study of Sphincter-Sparing Management of Adenocarcinoma of the Rectum
Glenn Steele, Jr, MD, PhD;
Paul Busse, MD, PhD;
Mark S. Huberman, MD;
Jean M. LeClair, RN;
Z. Myron Falchuk, MD;
Robert J. Mayer, MD;
Albert Bothe, Jr, MD;
Thanjavur S. Ravikumar, MD;
Michael Stone, MD;
J. Milburn Jessup, MD
Arch Surg. 1991;126(6):696-702.
Abstract
• After analysis of 26 prospectively accrued patients with distal rectal adenocarcinomas who underwent sphincter preservation treatment, we have concluded that tumors that invade only the submucosa can safely be treated with surgery alone and that tumors that invade the muscularis or further can be safely treated with surgery combined with chemoradiotherapy. None of the patients had either local or distant recurrence, with a median follow-up of 21 months. All patients have been fully continent. The results, although preliminary, imply that resection of distal rectal adenocarcinoma with sphincter preservation, and adjuvant therapy when appropriate, have achieved local and distant control equal to the conventional Miles' abdominoperineal resection, but without the need for a permanent colostomy.
(Arch Surg. 1991;126:696-702)
Author Affiliations
From the Departments of Surgery (Drs Steele, Bothe, Ravikumar, Stone, and Jessup and Ms LeClair), Medicine (Drs Huberman and Falchuk), and Radiation Therapy (Dr Busse), New England Deaconess Hospital, Harvard Medical School, and the Dana-Farber Cancer Institute (Drs Steele, Busse, Mayer, and Jessup), Boston, Mass, and the Department of Surgery, Yale University School of Medicine, New Haven, Conn (Dr Ravikumar).
Footnotes
Accepted for publication March 2, 1991.
Read before the 71st Annual Meeting of the New England Surgical Society, Newport, RI, September 14, 1990.
Reprint requests to New England Deaconess Hospital, 110 Francis St, Suite 3-A, Boston, MA 02215 (Dr Steele).
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