 |
|
Prognosis of Symptomatic Duodenal Adenomas in Familial Adenomatous Polyposis
P. Sue Beckwith, MD;
Jon A. van Heerden, MD;
Roger R. Dozois, MD
Arch Surg. 1991;126(7):825-828.
Abstract
| |
• The frequent association between familial adenomatous polyposis and duodenal tumors is increasingly recognized, yet many patients do not benefit from adequate diagnosis and follow-up of upper gastrointestinal polyps. A retrospective review of 14 patients with duodenal tumors associated with familial adenomatous polyposis was undertaken to assess the impact of early diagnosis by screening asymptomatic patients. Six of eight patients presenting with symptoms suggesting duodenal disease had invasive cancer. Four of these six patients died after surviving a mean of 13 months after diagnosis. In contrast, none of the six patients diagnosed after screening with upper gastrointestinal endoscopy has had invasive carcinoma. Early diagnosis and long-term surveillance of asymptomatic patients with familial adenomatous polyposis affords the opportunity to diagnose and treat duodenal tumors at an early stage, thereby, avoiding the dismal prognosis once invasive cancer has developed.
(Arch Surg. 1991;126:825-828)
Author Affiliations
From the Department of Surgery, Mayo Clinic, Rochester, Minn.
Footnotes
Accepted for publication March 9, 1991.
Read before the 98th Annual Meeting of the Western Surgical Association, Phoenix, Ariz, November 13, 1990.
Reprint requests to Department of Surgery, Mayo Clinic, 200 First St SW, Rochester, MN 55905 (Dr van Heerden).
 CiteULike  Connotea  Del.icio.us  Digg  Reddit  Technorati  Twitter
What's this?
THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES
Recurrent Pancreatitis in Gardner Variant Familial Polyposis: Etiology, Diagnostic Approach, and Interventional Results
Wright et al.
Arch Surg 1999;134:311-315.
ABSTRACT
| FULL TEXT
Bile and the Growth of Intestinal Polyps
Spigelman et al.
Arch Surg 1992;127:361-361.
ABSTRACT
|
