This Article  • References  • Full text PDF  • Send to a friend  • Save in My Folder  • Save to citation manager  • Permissions  Citing Articles  • Citation map  • Citing articles on HighWire  • Citing articles on Web of Science (66)  • Contact me when this article is cited  Related Content  • Similar articles in this journal  Social Bookmarking   What's this?

Dwijen C. Misra, Jr, MD; Geoffrey B. Blossom, MD; Darlene Fink-Bennett, MD; John L. Glover, MD

Arch Surg. 1991;126(8):957-960.

Abstract
• One hundred eighty-seven patients who presented with symptoms consistent with biliary colic but had no ultrasonic evidence of cholelithiasis were observed in an effort to identify those with a functional gallbladder disorder that might benefit from surgical intervention. All patients underwent quantitative evaluation of gallbladder emptying using cholecystokinin biliary scanning, and ejection fractions less than 35% were considered abnormal. One hundred twenty-nine patients (69%) had abnormal ejection fractions, and 88 (68%) of these subsequently underwent cholecystectomy. Sixty of the surgical specimens revealed pathologic changes. Eighty-four percent of patients successfully contacted for follow-up experienced complete relief, and another 13% had partial relief of preoperative symptoms. Only two patients reported no change in symptom complex. Twenty-nine patients with abnormal ejection fractions elected not to undergo surgery. Fifty-nine percent of these patients continued to experience symptoms of biliary colic at a mean follow-up of 22 months. Of the 44 patients with normal ejection fractions, 35 (80%) reported resolution of symptoms during follow-up of medical treatment. Cholecystokinin biliary scanning can help identify patients with acalculous, functional gallbladder disease who may benefit from cholecystectomy.

(Arch Surg. 1991;126:957-960)

Author Affiliations
From the Departments of Surgery (Drs Misra, Blossom, and Glover) and Nuclear Medicine (Dr Fink-Bennett), William Beaumont Hospital, Royal Oak, Mich.

Footnotes
Accepted for publication June 30, 1991.

Read before the 98th Annual Meeting of the Western Surgical Association, Scottsdale, Ariz, November 13, 1990.

Reprint requests to the Department of Surgery, William Beaumont Hospital, 3601 W Thirteen Mile Rd, Royal Oak, Ml 48073 (Dr Clover).

CiteULike    Connotea    Del.icio.us    Digg    Reddit    Technorati    Twitter     What's this?

THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES

Meta-analysis of Cholecystectomy in Symptomatic Patients With Positive Hepatobiliary Iminodiacetic Acid Scan Results Without Gallstones
Mahid et al.
Arch Surg 2009;144:180-187.
ABSTRACT | FULL TEXT  

The Use of Hepatobiliary Scintigraphy in Patients With Acalculous Biliary Colic
Halverson et al.
Arch Intern Med 1992;152:1305-1307.
ABSTRACT