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Initial Experience With 300 Patients

Julie S. Mitnick, MD; Madeline F. Vazquez, MD; Daniel F. Roses, MD; Matthew N. Harris, MD; Rosamond Gianutsos, PhD; Jerry Waisman, MD

Arch Surg. 1991;126(9):1137-1140.

Abstract
• The efficacy of stereotaxic aspiration biopsy was evaluated in 300 consecutive patients with nonpalpable mammographic lesions. Sixty-eight patients (23%) had suspicious or malignant aspirates; all cases were proved malignant by subsequent examination of operative specimens. Two hundred sixteen patients (72%) had benign aspirates. Of these, 65 were confirmed by operation and 151 had subsequent mammography at 6- and 12-month intervals with no demonstrable mammographic change. In 10 instances (3%), the aspirates were atypical, and in six (2%), nondiagnostic. Biopsy specimens were obtained in all 16 instances, and eight were malignant. The sensitivity of stereotaxic breast aspiration for the diagnosis of cancer was 96%, and the specificity was 100%. Our experience confirms the efficacy of stereotaxic aspiration for the initial evaluation of mammographically detected, nonpalpable lesions.

(Arch Surg. 1991;126:1137-1140)

Author Affiliations
From the Departments of Radiology (Dr Mitnick) and Pathology (Drs Vazquez and Waisman), and the Division of Oncology, Department of Surgery (Drs Roses and Harris), Kaplan Cancer Center, The Tisch Hospital, New York (NY) University Medical Center. Dr Gianutsos is a private consultant.

Footnotes
Accepted for publication March 23, 1991.

Reprint requests to New York University Medical Center, 530 First Ave, Suite 6E, New York, NY 10016 (Dr Roses).

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