Lung resection for colorectal metastases. 10-year results

P. M. McCormack, M. E. Burt, M. S. Bains, N. Martini, V. W. Rusch and R. J. Ginsberg
Department of Surgery, Memorial Sloan-Kettering Cancer Center, New York, NY 10021.

BACKGROUND--Metastasectomy for colorectal carcinoma to the lung is controversial. We analyzed results of this approach to justify its credibility. METHODS--We studied 144 patients by retrospective review after complete resection of lung metastases from colorectal cancer from 1965 through 1988. Patient selection and prognostic factors influencing survival were analyzed. Survival was analyzed by the Kaplan-Meier method, and comparisons were made by log-rank analysis. RESULTS--A total of 170 thoracotomies were performed in 144 patients. The overall 5- and 10-year survival was 40% and 30%, respectively. Those patients undergoing complete resection of their metastases survived significantly longer than those undergoing incomplete resections. CONCLUSION--It appears that resection of pulmonary metastases from colorectal carcinoma translates into long-term survival benefit.

THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES

Radiofrequency Ablation to Treat Non-Small Cell Lung Cancer and Pulmonary Metastases
Fernando
Ann. Thorac. Surg. 2008;85:S780-S784.
ABSTRACT | FULL TEXT  

Surgical Resection of Pulmonary Metastases From Colorectal Cancer: A Systematic Review of Published Series
Pfannschmidt et al.
Ann. Thorac. Surg. 2007;84:324-338.
ABSTRACT | FULL TEXT  

Treatment Failure After Percutaneous Radiofrequency Ablation for Nonsurgical Candidates With Pulmonary Metastases From Colorectal Carcinoma
Yan et al.
Ann. Surg. Oncol. 2007;14:1718-1726.
ABSTRACT | FULL TEXT  

Learning Curve for Percutaneous Radiofrequency Ablation of Pulmonary Metastases From Colorectal Carcinoma: A Prospective Study of 70 Consecutive Cases
Yan et al.
Ann. Surg. Oncol. 2006;13:1588-1595.
ABSTRACT | FULL TEXT  

Percutaneous Radiofrequency Ablation of Pulmonary Metastases from Colorectal Carcinoma: Prognostic Determinants for Survival
Yan et al.
Ann. Surg. Oncol. 2006;13:1529-1537.
ABSTRACT | FULL TEXT  

Surgical Management of Pulmonary Metastases from Colorectal Cancer in 153 Patients
Yedibela et al.
Ann. Surg. Oncol. 2006;13:1538-1544.
ABSTRACT | FULL TEXT  

Surgical Resection of Pulmonary Metastases From Colorectal Cancer: Four Favourable Prognostic Factors
Koga et al.
Jpn J Clin Oncol 2006;36:643-648.
ABSTRACT | FULL TEXT  

Chemotherapy permits resection of metastatic colorectal cancer: experience from Intergroup N9741
Delaunoit et al.
Ann Oncol 2005;16:425-429.
ABSTRACT | FULL TEXT  

Analysis of Surgical Salvage After Failure of Primary Therapy in Rectal Cancer: Results From Intergroup Study 0114
Tepper et al.
JCO 2003;21:3623-3628.
ABSTRACT | FULL TEXT  

Prognostic factors and survival after complete resection of pulmonary metastases from colorectal carcinoma: Experiences in 167 patients
Pfannschmidt et al.
J. Thorac. Cardiovasc. Surg. 2003;126:732-739.
ABSTRACT | FULL TEXT  

Chemoembolization of the Lung Improves Tumor Control in a Rat Model
Schneider et al.
Clin. Cancer Res. 2002;8:2463-2468.
ABSTRACT | FULL TEXT  

Intraoperative Lavage Cytologic Analysis of Surgical Margins as a Predictor of Local Recurrence in Pulmonary Metastasectomy
Higashiyama et al.
Arch Surg 2002;137:469-474.
ABSTRACT | FULL TEXT  

Surgical treatment of hepatic and pulmonary metastases from colon cancer
Headrick et al.
Ann. Thorac. Surg. 2001;71:975-980.
ABSTRACT | FULL TEXT  

Pulmonary metastasectomy
Zwischenberger and Alpard
Ann. Thorac. Surg. 1999;68:287-288.
FULL TEXT  

Thoracoscopic Resection of Solitary Lung Metastases From Colorectal Cancer Is a Viable Therapeutic Option
De Giacomo et al.
Chest 1999;115:1441-1443.
ABSTRACT | FULL TEXT  

Recommended Colorectal Cancer Surveillance Guidelines by the American Society of Clinical Oncology
Desch et al.
JCO 1999;17:1312-1312.
ABSTRACT | FULL TEXT  

Isolated Lung Perfusion With FUDR in the Rat: Pharmacokinetics and Survival
Port et al.
Ann. Thorac. Surg. 1996;62:848-852.
ABSTRACT | FULL TEXT  

Resection of Pulmonary Nodules Using Video-Assisted Thoracic Surgery
Bernard
Ann. Thorac. Surg. 1996;61:202-204.
ABSTRACT | FULL TEXT  

Isolated Lung Perfusion With FUDR Is an Effective Treatment for Colorectal Adenocarcinoma Lung Metastases in Rats
Ng et al.
Ann. Thorac. Surg. 1995;59:205-208.
ABSTRACT | FULL TEXT