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Jeffrey B. Matthews, MD; Hans U. Baer, MD; Walter P. Schweizer, MD; Philip Gertsch, MD; Thierey Carrel, MD; Leslie H. Blumgart, MD

Arch Surg. 1993;128(3):269-272.

Abstract
• We recently surgically treated 24 patients incapacitated by recurrent cholangitis after biliary-enteric anastomosis performed for benign disease. Contrary to commonly held dogma, as many as one third of the patients had no evidence of anastomotic stricture indicated by radiologic and operative findings. We identified several other primary and coexistent pathogenetic factors including intrahepatic stricture in 42% of the patients, intrahepatic calculi in 25%, improperly constructed enteric conduits in 13%, and conditions that predispose to bacterial overgrowth in the biliary tree in 17%. Seventy-one percent of the patients had multiple etiologic factors, and of those patients without demonstrable anastomotic stricture, intrahepatic stricture was particularly common. Seventy-one percent remained symptom-free in their first year after operation. The most difficult situation to manage, and the factor responsible for most recurrences after our reoperation, involved intrahepatic stricture. A combined surgical and interventional radiologic approach to complex cases may be useful in selected patients.

(Arch Surg. 1993;128:269-272)

Author Affiliations
From the Department of Surgery and Pancreaticobiliary Center, Beth Israel Hospital, Boston, Mass (Dr Matthews), and the Department of Visceral and Transplantation Surgery, University of Berne, Berne, Switzerland (Drs Baer, Schweizer, Gertsch, Carrel, and Blumgart).

Footnotes
Accepted for publication May 16, 1992.

Presented as part of a scientific symposium to honor William Silen, MD, at Beth Israel Hospital, Boston, Mass, May 16, 1991.

Reprint requests to Department of Surgery, Beth Israel Hospital, Boston, MA 02215 (Dr Matthews).

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