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  Vol. 131 No. 10, October 1996 TABLE OF CONTENTS
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Risk of Recurrent Biliary Tract Disease After Cholecystectomy in Patients With Duodenal Diverticula

Margaret E. Mackenzie, MD; Ward T. Davies, MD; Michael B. Farnell, MD; Amy L. Weaver, MS; Duane M. Ilstrup, MS

Arch Surg. 1996;131(10):1083-1085.


Abstract

Objective
To determine if the presence of duodenal diverticula predisposes to the development of common bile duct stones.

Design
Cohort study; median follow-up, 10.0 years (25th and 75th percentiles, 5.2 and 16.1 years, respectively).

Setting
Tertiary care center.

Patients
One hundred fifty-seven patients with radiologically diagnosed duodenal diverticula who had undergone cholecystectomy from 1950 through 1987 and were asymptomatic at the initiation of follow-up.

Main Outcome Measures
All patients were followed up for evidence of recurrent biliary tract disease to the following end points: (1) evidence of choledocholithiasis demonstrated by radiologic surgical, or biochemical means and (2) clinical or biochemical evidence of biliary pancreatitis

Results
Of the 157 patients in the study cohort, 13 patients were categorized as having had recurrent biliary tract disease. Using the Kaplan-Meier survivorship method, the cumulative probabilities of recurrent biliary tract disease in patients with radiologically diagnosed duodenal diverticula were 3.6% at 5 years (95% confidence interval, 0.5-6.9), 5.5% at 10 years (95% confidence interval, 1.5-9.4), and 10.2% at 15 years (95% confidence interval, 3.8-16.7). Age, common bile duct exploration and choledochotomy, and the presence of common bile duct dilatation were not found to be significantly associated with recurrence based on a univariate analysis of risk factors by means of the log-rank statistic.

Conclusions
For patients with radiologically diagnosed, second-portion duodenal diverticula, the risk of developing recurrent bile duct stones after cholecystectomy is lower than has been suggested in previous studies. In the absence of concurrent choledocholithiasis, sphincterotomy or biliary bypass at the time of cholecystectomy seems unwarranted.

Arch Surg. 1996;131:1083-1085



Author Affiliations

From the Department of Surgery, Division of Gastroenterologic and General Surgery (Drs Mackenzie, Davies, and Farnell), and Department of Health Sciences Research, Section of Biostatistics (Ms Weaver and Mr Ilstrup), Mayo Clinic, Rochester, Minn.



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