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Paul S. Dale, MD; Armando E. Giuliano, MD

Arch Surg. 1996;131(4):430-433.

Abstract
Objective
To determine if women with subareolar breast carcinoma can be successfully treated by breast-conserving therapy consisting of segmental mastectomy that preserves the nipple-areolar complex, axillary lymph node dissection, and postoperative irradiation.

Design
Prospective study.

Setting
Tertiary care cancer center.

Patients
Twenty-five patients; median age, 56 years; median tumor diameter, 1.4 cm; and median follow-up, 48 months.

Intervention
Breast-conserving therapy for subareolar primary breast carcinoma.

Results
Two patients had positive surgical margins of resection, and another patient underwent simple mastectomy after developing a local recurrence. Nipple-areolar distortion was the most common cosmetic deformity after breast-conserving therapy, but overall cosmesis was good. At the most recent follow-up, all patients were free of disease.

Conclusion
Patients who have small subareolar primary breast carcinomas without evidence of nipple involvement are candidates for breast-conserving therapy with nipple-areolar preservation.

(Arch Surg. 1996;131:430-433)

Author Affiliations
From the Joyce Eisenberg Keefer Breast Center of the John Wayne Cancer Institute at Saint John's Hospital and Health Center, Santa Monica, Calif.

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Breast Conservation Surgery Using Nipple-Areolar Resection for Central Breast Cancers
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Arch Surg 2004;139:32-37.
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