 |
 |

Endoscopic Ultrasound and Fine Needle Aspiration for the Evaluation of Pancreatic Masses
Jason Suits, BS;
Richard Frazee, MD;
Richard A. Erickson, MD
Arch Surg. 1999;134:639-643.
Hypothesis: Endoscopic ultrasound (EUS) and endoscopic ultrasoundguided fine needle aspiration (EUS-FNA) are accurate for the preoperative staging of pancreatic ductal carcinoma.
Design Retrospective medical record review.
Patients A prospective registry of 98 patients having EUS-FNA for peripancreatic masses from April 1994 to April 1998 was analyzed.
Main Outcome Measure The accuracy of EUS-FNA for preoperative diagnosis and staging of peripancreatic neoplasms.
Results Ninety-eight patients, aged 41 to 91 years (mean age, 67 years) with peripancreatic masses were evaluated by EUS-FNA. All patients had initial computed tomography scanning with a mass seen in 49 patients, "fullness" to the pancreas in 28 patients, and no mass seen in 21 patients. Evaluation with EUS-FNA revealed 22 benign lesions, 18 T2 masses, 37 T3 masses, 1 T4 mass, and 20 masses representing nonpancreatic tumors. Results of EUS-FNA of adjacent lymph nodes were positive in 27 patients. Twenty-seven patients had surgical resection or palliation permitting operative and pathologic staging. On comparison of EUS-FNA staging with surgical staging, 12 patients were the same stage, 14 patients were upstaged, and 1 patient was downstaged. The remaining patients who did not have surgery have been followed up for a mean of 15 months. Overall accuracy of EUS-FNA for differentiating benign from malignant masses was 96%.
Conclusions Endoscopic ultrasoundguided fine needle aspiration is a useful technique for the evaluation of pancreatic masses. It is highly accurate for differentiating between benign and malignant lesions and for predicting T stage, but is limited for predicting nodal status.
From the Departments of Surgery (Mr Suits and Dr Frazee) and Medicine (Dr Erickson), Scott & White Clinic and Memorial Hospital, Scott, Sherwood and Brindley Foundation, Texas A&M University Health Science Center, College of Medicine, Temple.
CiteULike Connotea Del.icio.us Digg Reddit Technorati Twitter
What's this?
THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES
Analysis of MicroRNAs in Pancreatic Fine-Needle Aspirates Can Classify Benign and Malignant Tissues
Szafranska et al.
Clin. Chem. 2008;54:1716-1724.
ABSTRACT
| FULL TEXT
My approach to pancreatic fine needle aspiration
Leiman
J. Clin. Pathol. 2007;60:43-49.
ABSTRACT
| FULL TEXT
Low Sensitivity of the ki-ras Polymerase Chain Reaction for Diagnosing Pancreatic Cancer From Pancreatic Juice and Bile: A Multicenter Prospective Trial
Trumper et al.
JCO 2002;20:4331-4337.
ABSTRACT
| FULL TEXT
The Use of Lajaroscoyqic Ultras onography in Staging Abdominal Malignancy
Goudas et al.
SURG INNOV 2000;7:78-86.
ABSTRACT
|