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Steven G. Friedman, MD; John S. Pellerito, MD; Larry Scher, MD; Glenn Faust, MD; Brian Burke, MD; Toufic Safa, MD

Arch Surg. 2002;137:462-464.

Hypothesis  Ultrasound-guided injection of thrombin is the treatment of choice for femoral pseudoaneurysms.

Design  A prospective study of patients undergoing a single form of treatment for femoral pseudoaneurysms.

Setting  Patients were treated at 2 tertiary care, university-affiliated hospitals.

Patients  Forty consecutive patients with femoral pseudoaneurysms resulting from diagnostic and therapeutic catheterizations for peripheral arterial, coronary arterial, and cerebrovascular diseases were evaluated.

Intervention  Thrombin was injected directly into the pseudoaneurysms under ultrasonographic guidance.

Main Outcome Measure  Thrombosis of the pseudoaneurysm following thrombin injection was the goal of treatment.

Results  All 40 patients had initial complete thrombosis of their femoral pseudoaneurysms. In each case, except for one, the aneurysm was noted to have thrombosed on follow-up duplex ultrasongram. There was one complication.

Conclusion  Ultrasound-guided thrombin injection is the treatment of choice for femoral pseudoaneurysms.

From the Division of Vascular Surgery (Drs Friedman, Scher, and Safa) and Department of Radiology (Drs Pellerito and Burke), North Shore University Hospital, Manhasset, NY, and the Division of Vascular Surgery, Long Island Jewish Medical Center, New Hyde Park, NY (Dr Faust).

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