This Article  • Full text  • PDF  • Send to a friend  • Save in My Folder  • Save to citation manager  • Permissions  Citing Articles  • Citation map  • Citing articles on HighWire  • Citing articles on ISI (12)  • Contact me when this article is cited  Related Content  • Related articles  • Similar articles in this journal  Topic Collections  • Lung Cancer  • Pulmonary Diseases, Other  • Surgical Oncology  • Radiography  • Alert me on articles by topic  Social Bookmarking   What's this?

Jeffrey P. Lamont, MD; James T. Kakuda, MD; David Smith, PhD; Lawrence D. Wagman, MD; Frederic W. Grannis, Jr, MD

Arch Surg. 2002;137:935-939.

Hypothesis  Systematic postoperative evaluation of patients with non–small cell lung cancer will identify treatable second primary lung cancer and local recurrences.

Design  Retrospective review from January 1, 1996, to December 31, 2000. The follow-up protocol included an annual computed tomographic examination of the chest with interval chest radiography every 4 months for 2 years and every 6 months for 3 additional years.

Setting  A National Cancer Institute–designated comprehensive cancer center.

Patients  One hundred twenty-four patients with resected non–small cell lung cancer.

Main Outcome Measures  Number and size of second primary and locally recurrent tumors, secondary surgical procedures, and survival of patients who underwent resection.

Results  The median diameter of resected second primary tumors detected by computed tomography was 14 mm (range, 8-28 mm) and by chest radiography was 26.5 mm (range, 23.0-35.0 mm) (P<.001). Of 14 patients with second primary lung cancer treated surgically, 9 were without evidence of disease at a median of 20 months (range, 4-56 months), 2 were alive with disease at 13 and 37 months, 2 died of unrelated causes but without evidence of disease at 7 and 35 months, and 1 died intraoperatively of a cardiac arrhythmia.

Conclusions  Systematic follow-up of non–small cell lung cancer, including annual computed tomography, detects second primary lung cancer in stage IA. Limited pulmonary resections are often feasible in these patients. Locally recurrent lung cancer is infrequently resectable.

From the Division of Surgery, Department of General and Oncologic Surgery (Drs Lamont, Kakuda, Wagman, and Grannis), and the Department of Biostatistics (Dr Smith), City of Hope National Medical Center, Duarte, Calif.

CiteULike    Connotea    Del.icio.us    Digg    Reddit    Technorati     What's this?

RELATED ARTICLES

This Month in Archives of Surgery
Arch Surg. 2002;137(8):881.
FULL TEXT  

Systematic Postoperative Radiologic Follow-up in Patients With Non–Small Cell Lung Cancer for Detecting Second Primary Lung Cancer in Stage IA—Invited Critique
John R. Benfield
Arch Surg. 2002;137(8):940.
EXTRACT | FULL TEXT  

THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES

Follow-up and Surveillance of the Lung Cancer Patient Following Curative Intent Therapy: ACCP Evidence-Based Clinical Practice Guideline (2nd Edition)
Rubins et al.
Chest 2007;132:355S-367S.
ABSTRACT | FULL TEXT  

Imaging of the Patient with Non-Small Cell Lung Cancer
Munden et al.
Radiology 2005;237:803-818.
ABSTRACT | FULL TEXT  

Cost Effectiveness of Chest Computed Tomography After Lung Cancer Resection: A Decision Analysis Model
Kent et al.
Ann. Thorac. Surg. 2005;80:1215-1223.
ABSTRACT | FULL TEXT  

Surveillance computed tomography after complete resection for non-small cell lung cancer: Results and costs
Korst et al.
J. Thorac. Cardiovasc. Surg. 2005;129:652-660.
ABSTRACT | FULL TEXT