This Article  • Full text  • PDF  • Send to a friend  • Save in My Folder  • Save to citation manager  • Permissions  Citing Articles  • Citation map  • Citing articles on HighWire  • Citing articles on ISI (17)  • Contact me when this article is cited  Related Content  • Similar articles in this journal  Topic Collections  • Bacterial Infections  • Colon Cancer  • Surgical Oncology  • Surgical Physiology, Other  • Infectious Diseases  • Alert me on articles by topic  Social Bookmarking   What's this?

Jason S. Gold, MD; Sancar Bayar, MD; Ronald R. Salem, MD

Arch Surg. 2004;139:760-765.

Background  The association between Streptococcus bovis bacteremia and colonic neoplasia is well described; however, the relationship between S bovis and neoplasia outside the colon has not been well evaluated.

Hypothesis  S bovis bacteremia may be associated with colonic neoplasia and extracolonic malignancy.

Design  Retrospective review of all documented cases of S bovis bacteremia identified by a search of computerized bacteriology records.

Setting  One tertiary referral hospital and 1 community hospital located in the same city.

Patients  Forty-five patients (41 adults, 4 children) with documented S bovis bacteremia during a 12-year period were identified.

Main Outcome Measures  Available patient records were reviewed to identify the presence of colonic neoplasia, the use of gastrointestinal endoscopy, and the presence of gastrointestinal or extraintestinal malignancies.

Results  Seventeen patients (41% of adult patients) underwent colonoscopy. Colonic neoplasia was present in 16 patients (39% of adults), with 3 of these patients having invasive colorectal cancer (7% of adults). Invasive cancer was present in 13 patients (32% of adults). Eight patients had malignant lesions arising within the gastrointestinal tract, and 5 patients had extraintestinal malignancies.

Conclusion  S bovis bacteremia is associated with both colonic neoplasia and extracolonic malignancy.

From the Department of Surgery, Yale University School of Medicine, New Haven, Conn.

CiteULike    Connotea    Del.icio.us    Digg    Reddit    Technorati     What's this?

THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES

Infectious Agents and Colorectal Cancer: A Review of Helicobacter pylori, Streptococcus bovis, JC Virus, and Human Papillomavirus
Burnett-Hartman et al.
Cancer Epidemiol. Biomarkers Prev. 2008;17:2970-2979.
ABSTRACT | FULL TEXT  

A Stitch in Time -- A 64-year-old man with a history of coronary artery disease and peripheral vascular disease was admitted to the hospital with a several-month history of fevers, chills, and fatigue
Graber et al.
NEJM 2007;357:1029-1034.
FULL TEXT  

Bioproduction of Conjugated Linoleic Acid by Probiotic Bacteria Occurs In Vitro and In Vivo in Mice
Ewaschuk et al.
J. Nutr. 2006;136:1483-1487.
ABSTRACT | FULL TEXT  

Viable Bacteria Present within Oral Squamous Cell Carcinoma Tissue.
Hooper et al.
J. Clin. Microbiol. 2006;44:1719-1725.
ABSTRACT | FULL TEXT  

Use of Phylogenetic and Phenotypic Analyses To Identify Nonhemolytic Streptococci Isolated from Bacteremic Patients
Hoshino et al.
J. Clin. Microbiol. 2005;43:6073-6085.
ABSTRACT | FULL TEXT