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Unveiling a Hidden Entity

Michael Wayne, DO; Keith A. Delman, MD; Tolga Kurt, MD; Robert Grossi, MD; Maria Sabatini, MD; Avram Cooperman, MD

Arch Surg. 2005;140:1104-1107.

Hypothesis  After alcohol-induced and hereditary disease, idiopathic chronic pancreatitis is the most common cause of calcifying pancreatitis. This designation is used when no associated cause of chronic pancreatitis is found. We present 6 cases of idiopathic pancreatitis in which the postoperative pathological examination results demonstrated lymphoplasmacytic sclerosing pancreatitis or autoimmune pancreatitis.

Design  Retrospective case series. The medical records of 6 patients referred and treated for autoimmune pancreatitis were reviewed. The duration of follow-up varies, the longest being 5 years. The disease and a literature review are reported.

Setting  A 200-bed community hospital located in a large city. The patients were referred after being treated elsewhere for recurrent pancreatitis.

Patients and Methods  Six patients with chronic recurrent pancreatitis were evaluated. They were selected because pathological review indicated that they all had autoimmune pancreatitis.

Results  Six cases of lymphoplasmacytic sclerosing pancreatitis are presented and suggest that lymphoplasmacytic sclerosing pancreatitis should be thought of more often in chronic autoimmune pancreatitis.

Conclusion  Lymphoplasmacytic sclerosing pancreatitis is an increasingly recognized cause of chronic pancreatitis and should be considered in the evaluation of patients with chronic pancreatitis and no discernible cause.

Author Affiliations: The Center for Biliary and Pancreatic Surgery at Cabrini Medical Center, Departments of Surgery (Drs Wayne, Kurt, Grossi, and Cooperman) and Pathology (Dr Sabatini) at Cabrini Medical Center, New York, NY, and Department of Surgery Montefiore Medical Center, Albert Einstein College of Medicine, New York, NY (Dr Delman).

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