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Report of 2 Cases

Fernando D. Hayetian, MD; Thomas E. Read, MD; Marc Brozovich, MD; Robert P. Garvin, MD; Philip F. Caushaj, MD

Arch Surg. 2006;141:97-99.

Two cases of small-bowel perforation secondary to Clostridium difficile enteritis are described and compared with the 8 cases of C difficile enteritis reported in the medical literature. The cause of small-bowel involvement with C difficile is unknown, but prior antibiotic use, prior colectomy, chronic alterations in small-bowel flora, and other host factors are discussed.

Author Affiliations: Division of Colon and Rectal Surgery, The Western Pennsylvania Hospital, Clinical Campus of Temple University School of Medicine, Pittsburgh.