 |
|
Primary Hyperaldosteronism
Effect of Adrenal Vein Sampling on Surgical Outcome
Fiemu E. Nwariaku, MD;
Barbra S. Miller, MD;
Richard Auchus, MD, PhD;
Shelby Holt, MD;
Lori Watumull, MD;
Bart Dolmatch, MD;
Shawna Nesbitt, MD;
Wanpen Vongpatanasin, MD;
Ronald Victor, MD;
Frank Wians, PhD;
Edward Livingston, MD;
William H. Snyder III, MD
Arch Surg. 2006;141:497-503.
Hypothesis Adrenal vein sampling is superior to computed tomography for subtype differentiation of primary hyperaldosteronism.
Design Retrospective review.
Setting University medical center.
Patients Forty-eight patients (32 men and 16 women) with biochemically confirmed primary hyperaldosteronism.
Main Outcome Measures We compared demographic factors, results of biochemical and imaging studies (computed tomography and adrenal vein sampling), therapy, and patient outcomes.
Results Mean ± SEM adrenal nodule size was 1.54 ± 0.2 cm. Adrenal vein sampling was performed in 41 (85%) of 48 patients, and it was successful in 39 (95%) of those 41 patients. Concordance between computed tomography and adrenal vein sampling was observed in 22 (54%) of the 41 patients. Thirty-two patients underwent successful laparoscopic adrenalectomy. There was 1 complication and no deaths. All 32 patients were cured of hypokalemia.
Conclusion Adrenal vein sampling is superior to image-based techniques for subtype differentiation of primary hyperaldosteronism.
Author Affiliations: Departments of Surgery (Drs Nwariaku, Miller, Holt, Livingston, and Snyder), Medicine (Drs Auchus, Nesbitt, Vongpatanasin, and Victor), Radiology (Drs Watumull and Dolmatch), and Pathology (Dr Wians), University of Texas Southwestern Medical Center, Dallas.
THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES
Will the Lessons From Primary Aldosteronism Change the Treatment of Hypertension and Left Ventricular Hypertrophy?
Auchus and Drazner
Hypertension 2007;50:837-839.
FULL TEXT
Is There an Unrecognized Epidemic of Primary Aldosteronism? (Pro)
Calhoun and Kaplan
Hypertension 2007;50:447-453.
FULL TEXT
Is There an Unrecognized Epidemic of Primary Aldosteronism? (Con)
Kaplan and Calhoun
Hypertension 2007;50:454-458.
FULL TEXT
Measurement of 18-Hydroxycorticosterone during Adrenal Vein Sampling for Primary Aldosteronism
Auchus et al.
J. Clin. Endocrinol. Metab. 2007;92:2648-2651.
ABSTRACT
| FULL TEXT
|
