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  Vol. 142 No. 1, January 2007 TABLE OF CONTENTS
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Long-term Results of Endovascular Abdominal Aortic Aneurysm Treatment With the First Generation of Commercially Available Stent Grafts

Lina J. Leurs, MSc; Jacob Buth, MD, PhD; Robert J. F. Laheij, PhD; for the EUROSTAR Collaborators

Arch Surg. 2007;142(1):33-41.

Hypothesis  Little information about the long-term results of endovascular abdominal aortic aneurysm repair is available. This study was performed to evaluate the long-term data of patients treated with the first generation of commercially available stent grafts.

Design  Multicenter registry.

Setting  Sixty-two European centers that participated in the EUROSTAR (EUROpean collaborators on Stent-graft Techniques for abdominal aortic Aneurysm Repair) registry.

Patients  A total of 1190 patients with a follow-up of up to 8 years, who underwent endovascular abdominal aortic aneurysm repair with a stent graft (Stentor or Vanguard).

Intervention  Elective endovascular abdominal aortic aneurysm repair.

Main Outcome Measures  The morbidity and mortality data of patients treated with the first-generation stent graft who enrolled in the EUROSTAR registry were analyzed. Incidence rates of complications were calculated to quantify annual risks. Life-table analyses and multivariate Cox proportional hazards models were used for the survival analysis.

Results  Conversion to open repair, aneurysm rupture, all-cause death, and aneurysm-related death occurred in 7.1%, 2.4%, 19.9%, and 3.0% of the patients, respectively. The cumulative percentage of the combined outcome event, conversion-free and rupture-free survival, after 8 years was 48.0%. Procedure-related complications that frequently occurred were endoleak (13.0 cases per 100 patient-years), stenosis/thrombosis (4.6 cases per 100 patient-years), and stent migration (4.3 cases per 100 patient-years).

Conclusions  Patients treated with the first generation of stent grafts will need lifelong surveillance because of a considerable risk of late complications. How these findings translate to the outcome of newer-generation stent grafts is unknown. For this reason, vigilant surveillance remains indicated in all patients who undergo endovascular abdominal aortic aneurysm repair.


Author Affiliations: EUROSTAR Data Registry Centre, Department of Vascular Surgery, Catharina Hospital, Eindhoven, the Netherlands.



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RELATED ARTICLE

Long-term Results of Endovascular Abdominal Aortic Aneurysm Treatment With the First Generation of Commercially Available Stent Grafts—Invited Critique
Jon S. Matsumura
Arch Surg. 2007;142(1):42.
EXTRACT | FULL TEXT  


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES

Aortic Coarctation Secondary to In-Stent Stenosis of a Covered Aortic Endoprosthesis
Akowuah et al.
Ann. Thorac. Surg. 2008;85:2142-2142.
FULL TEXT  

Endovascular infrarenal abdominal aortic aneurysm repair
Davis and Taylor
Heart 2008;94:222-228.
ABSTRACT | FULL TEXT  





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