Yttrium 90 Microsphere Selective Internal Radiation Treatment of Hepatic Colorectal Metastases
Seza A. Gulec, MD;
Yuman Fong, MD
Arch Surg. 2007;142(7):675-682.
Objective To discuss the basic concepts involved in the development of yttrium 90 (Y-90) microsphere selective internal radiation treatment and review the clinical data pertaining to its application in hepatic colorectal cancer metastases.
Data Sources Published studies and scientific paper presentations.
Study Selection Randomized clinical studies and retrospective reviews.
Conclusions Selective internal radiation treatment is a promising new modality in the treatment of patients with hepatic colorectal cancer metastases as part of a multimodality approach. A chemo–selective internal radiation treatment neoadjuvant approach has a potential to improve therapeutic outcomes. Clinical studies in neoadjuvant and salvage settings are needed for more concrete outcome data and design of optimal multimodality treatment strategies.
Author Affiliations: Center for Cancer Care at Goshen Health System, Goshen, Indiana (Dr Gulec); and Memorial Sloan Kettering Cancer Center, New York, New York (Dr Fong)
RELATED LETTER
Yttrium 90 Microsphere Selective Internal Radiation Treatment of Hepatic Colorectal Metastases
Timothy J. Price and Amanda Townsend
Arch Surg. 2008;143(3):313-314.
EXTRACT
| FULL TEXT
THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES
Yttrium 90 Microsphere Selective Internal Radiation Treatment of Hepatic Colorectal Metastases
Price and Townsend
Arch Surg 2008;143:313-314.
FULL TEXT
Posttherapy Radiation Safety Considerations in Radiomicrosphere Treatment with 90Y-Microspheres
Gulec and Siegel
JNM 2007;48:2080-2086.
ABSTRACT
| FULL TEXT
|
