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Translational Research in Surgical Disease
Alexander Stojadinovic, MD;
Nita Ahuja, MD;
Susanna M. Nazarian, MD, PhD;
Dorry L. Segev, MD;
Lisa Jacobs, MD;
Yongchun Wang, MD;
John Eberhardt, MD;
Martha A. Zeiger, MD
Arch Surg. 2010;145(2):187-196.
Objective To review cutting-edge, novel, implemented and potential translational research and to provide a glimpse into rich, innovative, and brilliant approaches to everyday surgical problems.
Data Sources Scientific literature and unpublished results.
Study Selection Articles reviewed were chosen based on innovation and application to surgical diseases.
Data Extraction Each section was written by a surgeon familiar with cutting-edge and novel research in their field of expertise and interest.
Data Synthesis Articles that met criteria were summarized in the manuscript.
Conclusions Multiple avenues have been used for the discovery of improved means of diagnosis, treatment, and overall management of patients with surgical diseases. These avenues have incorporated the use of genomics, electrical impedence, statistical and mathematical modeling, and immunology.
Author Affiliations: Division of Surgical Oncology, Department of Surgery, Walter Reed Army Medical Center, Washington, DC (Dr Stojadinovic); Division of Endocrine and Surgical Oncology (Drs Ahuja, Jacobs, Wang, and Zeiger), Division of Vascular Surgery (Dr Nazarian), and Division of Transplantation (Dr Segev), Department of Surgery, The Johns Hopkins University School of Medicine, Baltimore, Maryland; and Healthcare DecisionQ Corporation, Washington, DC (Dr Eberhardt).
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