THE CALL from a junior medical resident at Lakeside Hospital in Cleveland, Ohio, was puzzling.
"We have a 55-year-old lady with a serum cholesterol of 600 mg percent because there is a stone blocking her common bile duct!"
"Is she jaundiced?"
"Not at all. The stone is causing cholesterol to back up."
I had learned by the time I was chief resident, in 1964, not to play 20 questions with referring doctors. Stifling incredulity, I replied, "I'll be right there."
Findings from the cholangiogram showed an enlarged common bile duct with a large stone; there was no bilirubinemia, and alkaline phosphatase levels were moderately elevated. Her gallbladder had been removed leaving a long cystic duct stump. After choledochotomy and T-tube drainage, the laboratory head graciously honored my unusual request for daily serum cholesterol levels.
Over the next 10 days, the serum cholesterol fell to a level of 140 mg/dL and . . . [Full Text of this Article]