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A Personal Perspective on the Current Status of Sentinel Lymph Node Dissection for Breast Cancer

Armando E. Giuliano, MD
Santa Monica, Calif

Arch Surg. 1999;134:195-199.

	Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings.

IN 1972, Haagensen¹ illustrated the axillary nodal uptake of a vital blue dye during mastectomy. In 1977 Cabanas² described the identification of nodal drainage pathways and a sentinel node (SN) from penile cancer. Fifteen years later, at the John Wayne Cancer Institute in Santa Monica, Calif, Morton et al³ introduced intraoperative lymphatic mapping as a minimally invasive, practical means of identifying regional nodal metastases to eliminate routine lymph node dissection in patients with no evidence of metastases from cutaneous melanoma. Our group at the John Wayne Cancer Institute popularized the concept of an SN as the first regional lymph node to receive tumor cells that metastasize along the lymphatic drainage pathway from a primary tumor. The tumor status of this SN should therefore reflect the tumor status of the entire regional lymphatic drainage basin.

In October 1991, we began to test the feasibility of intraoperative lymphatic . . . [Full Text of this Article]

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