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  Vol. 136 No. 5, May 2001 TABLE OF CONTENTS
  Archives
  •  Online Features
  Correspondence and Brief Communications
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Elucidation of Active Anticancer Agents in Naturally Occurring Substances

Arch Surg. 2001;136:600.

Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings.

In their concise study using an allogeneic model, Hamzaolu et al1 provide evidence that Ehrlich ascites tumor implantation is inhibited by the prior and concurrent local injection of honey. The authors propose that this method of tumor implant prevention may be applicable to the prevention of tumor in surgical wounds, particularly those wounds created during laparoscopic procedures. Tumor implantation in such wounds has complicated the management of colorectal cancer and gallbladder carcinoma.

This is yet another example of the application of naturally occurring substances in medicine. Although one may quibble with the details of this allogeneic model and the method of tumor manipulation, the results provide evidence that the manipulation of the wound as described by the authors has the ability to prevent successful metastasis in their model. However, as with many naturally derived substances, whether their use has been defined through folk medicine, serendipitous observation, or by the identification . . . [Full Text of this Article]



THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES

Honey in Tumor Surgery
Facino
Arch Surg 2004;139:802-802.
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