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Image of the MonthDiagnosis
Arch Surg. 2004;139:224.
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Answer: Desmoid Tumor
Figure 1. Computed tomographic scan of the abdomen and pelvis demonstrating a large, homogeneous mass of approximately 23 x 15 cm.
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Figure 2. Biopsy specimen taken from the intra-abdominal tumor showing the same appearance as the incisional biopsy specimens taken from the mesentery: a paucicellular to cellular proliferation of bland-looking fibroblasts, infiltrating muscle and engulfing muscle fibers (black arrowheads). No mitoses are seen. Immunohistochemical analysis was negative for CD117 (poly C-kit) and estrogen receptors but weakly positive for progesterone receptors.
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Desmoid tumors are benign in origin and do not metastasize. However, they can be aggressive locally and have a tendency for local recurrence after excision.1-2 Their ability for local infiltration can result in significant deformity, morbidity, and mortality. Desmoid tumors in the general population are rare, accounting for 0.03% of all neoplasms.3-4 There is an association between the occurrence of desmoid tumors and familial . . . [Full Text of this Article]
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Arch Surg. 2004;139(2):223.
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