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Applicability of Tissue Aspirate for Quick Parathyroid Hormone Assay to Confirm Parathyroid Tissue Identity During Parathyroidectomy for Primary Hyperparathyroidism—Invited Critique
Jack M. Monchik, MD
Arch Surg. 2005;140:150.
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| Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings. |
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This study shows that the measurement of intact PTH levels obtained from aspiration of tissue excised during surgery for hyperparathyroidism is highly specific for parathyroid tissue. The additional cost for the tissue assay when intraoperative monitoring of serum intact PTH level is used is less than the cost of a frozen section analysis. The authors state that this would allow a more selective use of frozen section analysis during parathyroid surgery. However, frozen section analysis is rarely needed when a localized hyperfunctioning gland with a typical gross appearance is removed and an appropriate decrease in serum intact PTH is seen. This is particularly true if the hyperfunctioning gland is localized to the same anatomic site, shown by both technetium Tc 99m sestamibi scintigraphy and ultrasonography. A typical hyperfunctioning parathyroid gland is soft and reddish or tan. However, all hyperfunctioning glands do not have this typical appearance. . . . [Full Text of this Article]
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Applicability of Tissue Aspirate for Quick Parathyroid Hormone Assay to Confirm Parathyroid Tissue Identity During Parathyroidectomy for Primary Hyperparathyroidism
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