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Image of the MonthDiagnosis
Arch Surg. 2005;140:810.
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Answer: Angiosarcoma of the Breast
At the time of mastectomy, a cutaneous nodule emerged (Figure 1). The magnetic resonance image shows enhancement of diffuse skin thickening with evidence of extension into the subareolar tissue (Figure 2). A total mastectomy with axillary lymph node dissection was performed (the latter was based on the erroneous preoperative diagnosis of ductal carcinoma). The final pathological results revealed poorly differentiated angiosarcoma both medial to the nipple and in the lower outer quadrant.
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Figure 1: Photograph of the left breast. Ruler units are centimeters.
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Figure 2: Gadolinium-enhanced magnetic resonance image of the left breast.
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Angiosarcoma of the breast that arises in the absence of known risk factors, termed primary angiosarcoma, represents less than 1% of all primary breast malignancies and 3% to 10% of all breast sarcomas.1 In general, the disease is considered to be rare.2 It is more prevalent in younger populations and is most often . . . [Full Text of this Article]
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