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Image of the MonthDiagnosis
Arch Surg. 2005;140:912-913.
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Answer: Heterotopic (Ectopic) Pancreas of Ileum
On opening the surgical specimen, the center portion of the lobulated nodule showed the presence of umbilication. Light microscopy showed that the lesion was located in the submucosa of the ileum and was composed of pancreatic acinar cells, pancreatic ducts, and islets of Langerhans (Figure 1 and Figure 2). No malignant transformation was found. The mucosal and serosal surfaces of the ileum were normal. The pathological diagnosis was heterotopic (ectopic) pancreas of the ileum.
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Figure 1. The lesion, situated within the submucosa of the ileum, shows evidence of pancreatic ducts and acinar cells. Ileum mucosa is visible at the lower right (hematoxylin-eosin, x100).
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Figure appears in full text version.
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Figure 2. Histological specimen of the lesion, which is composed of pancreatic ducts, acinar cells, and islets of Langerhans (hematoxylin-eosin, x100).
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Heterotopic, ectopic, or aberrant pancreatic tissue, also known as a pancreatic rest, is an uncommon congenital anomaly defined as extra pancreatic tissue . . . [Full Text of this Article]
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Bo-Guang Fan, Fa-Biao Zhang, Mei-Fu Gan, and Åke Andrén-Sandberg
Arch Surg. 2005;140(9):911.
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