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  Vol. 141 No. 1, January 2006 TABLE OF CONTENTS
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Venous Bicarbonate Correlates Linearly With Arterial Base Deficit Only If pH Is Constant

Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings.

Martin et al1 retrospectively studied more than 2000 nontrauma-related surgical ICU admissions and reported that serum bicarbonate (HCO3) might provide information equivalent to the arterial base deficit (BD). This conclusion is a bit surprising, as is their determination that the normal BD of 0 is associated with an HCO3 level of 22 mEq/L rather than the typical level of 24.

There are many formulae2 to calculate the BD, or its negative, the base excess (BE). A positive BE, or a negative BD, is typically associated with an increased serum bicarbonate level, so the authors may have confused these 2 terms. Digital blood gas analyzers today are unlikely to use the standard nomograms, and perhaps the simplest formula for BE is given by the point-of-care blood analyzers (iSTAT Corp, East Windsor, NJ) now used in our hospital: BE = (HCO3) – 24.8 + 16.2 x (pH – 7.4).

This equation may clearly indicate that there is expected . . . [Full Text of this Article]


AUTHOR INFORMATION
Eugenio Lujan, MD; Red Howard, MD, PhD


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