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Martin A. Makary, MD, MPH

Arch Surg. 2006;141:1114.

	Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings.

Rates of SSI are emerging as the leading indicator of quality in surgery. The Center for Medicare & Medicaid Services recently announced its plan to use SSI rates to adjust payments (aka pay-for-performance). Attention on SSI as a surrogate of quality, combined with the growing problem of antibiotic-induced resistance, has brought the issue of prophylaxis to the center stage. This study of 12 299 elective surgical patients found that single-dose antibiotic prophylaxis resulted in the same incidence of SSI as 24-hour dosing and concluded that single-dose administration is equivalent, cheaper, and achievable at a high-volume center. Inherent in their findings is an advocacy for the judicious use of antibiotics—a timely message given a long history of overuse within our profession.

Although this study challenges routine 24-hour antibiotic dosing, it was limited in its follow-up, complete in only 47% of patients and performed over the telephone as . . . [Full Text of this Article]

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Implementing 1-Dose Antibiotic Prophylaxis for Prevention of Surgical Site Infection
Silvia Nunes Szente Fonseca, Sônia Regina Melon Kunzle, Maria José Junqueira, Renata Teodoro Nascimento, José Ivan de Andrade, and Anna S. Levin
Arch Surg. 2006;141(11):1109-1113.
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