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Sherry M. Wren, MD

Arch Surg. 2006;141:1227.

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This article reports a single institution's experience with PET or PET-CT in patients referred for surgical treatment of hepatic metastases. During a 3-year period, 71 patients who were judged operative candidates by CDMs underwent PET. Detection of hepatic lesions was 100% by CDMs, but PET had only a 90% concordance rate, missing 7 patients' disease. False-negative findings were more likely to be at the dome of the liver or in lesions less than 3 cm in size. Positron emission tomography identified additional disease in 32% of the cases, with more than half of those (13/23) in extra-abdominal locations. The impact of PET on clinical decision making was difficult to fully evaluate. The authors report that a total of 17 patients (24%) had their management altered on the basis of PET findings, but then tack on an additional 8 patients whose PET findings were ignored or further . . . [Full Text of this Article]

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