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Herbert Chen, MD

Arch Surg. 2006;141:134.

	Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings.

Intraoperative PTH testing has revolutionized the way we treat patients with primary hyperparathyroidism (HPT) by allowing focused, "minimally invasive" procedures targeting resection of a single parathyroid adenoma.¹ As shown by Irvin et al, Udelsman et al, our group, and others, intraoperative PTH testing (with first-generation assays) allows detection and subsequent resection of additional hyperfunctioning parathyroid glands intraoperatively, thereby improving cure rates following parathyroidectomy.^2-5 Although the importance of intraoperative PTH testing in patients with primary HPT has been defined, its role in patients with secondary HPT is unclear.

Dr Kaczirek and colleagues have published very important studies addressing this issue. In an article published in the April 2005 issue of Surgery,⁶ the authors studied 35 patients with renal HPT undergoing parathyroidectomy and reported that first-generation intraoperative PTH assays were not useful to predict cure following surgery. This is presumably because first-generation intraoperative PTH assays can be falsely . . . [Full Text of this Article]

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Novel Parathyroid Hormone (1-84) Assay as Basis for Parathyroid Hormone Monitoring in Renal Hyperparathyroidism
Klaus Kaczirek, Gerhard Prager, Philipp Riss, Gerald Wunderer, Reza Asari, Christian Scheuba, Christian Bieglmayer, and Bruno Niederle
Arch Surg. 2006;141(2):129-134.
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