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Richard J. Bold, MD

Arch Surg. 2006;141:695.

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Capussotti et al review the incidence of bile leakage complicating liver surgery in 610 patients who underwent a variety of hepatic resections for various indications. They observed a low incidence of this complication (22 [3.6%] of 610 patients), although it was associated with more than doubling the length of hospitalization but was not associated with increased secondary morbidity or mortality. The authors examined a variety of patient, disease, and technical factors associated with the development of this operative complication; resection of segment 4 and the diagnosis of peripheral cholangiocarcinoma were associated with an increased risk of bile leakage, whereas treatment of the cut hepatic surface with fibrin glue was associated with a decreased risk. The authors conducted the study to identify risk factors that could be modified and therefore reduce the incidence of this complication. Unfortunately, 2 of the 3 risk factors (namely, the diagnosis of . . . [Full Text of this Article]

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Bile Leakage and Liver Resection: Where Is the Risk?
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