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Intraductal Papillary Mucinous Neoplasm of the Pancreas and Associated Lesions
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We read with great interest the recent publication in the Archives of Surgery regarding extrapancreatic neoplasms in patients with intraductal papillary mucinous neoplasms (IPMNs).1 In analyzing the tumors that the authors have suggested to be putatively associated with IPMN, we note that several of the benign tumors could be owing to serendipity. This is particularly true of extragastrointestinal neoplasms such as thyroid adenoma, ovarian mucinous cystadenoma, and meningioma. In addition, the occurrence of a tubular adenoma as well as a solitary case of gastrointestinal stromal tumor may also be construed in a similar light. With regard to the malignant lesions, there may indeed be an association between the gastrointestinal carcinomas described and IPMN.
Of particular interest to us is the possible association between IPMN and familial adenomatous polyposis and attenuated familial adenomatous polyposis. We have documented the occurrence of IPMN in a patient with attenuated familial adenomatous polyposis.2 The patient . . . [Full Text of this Article] AUTHOR INFORMATION
Runjan Chetty, MB, BCh, FRCPath, FRCPC, DPhil;
Stefano Serra, MD
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