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Are Single-Dose Preoperative Antibiotic Regimens Really Appropriate?—Reply
Silvia Nunes Szente Fonseca, MD, MPH;
Sônia Regina Melon Kunzle, RN;
Maria José Junqueira, RN;
Renata Teodoro Nascimento, MD;
José Ivan de Andrade, MD, PhD;
Anna Sara Shafferman Levin, MD, PhD
Arch Surg. 2007;142(6):577.
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In reply
We read with interest the comments by Dr Schmidt and feel that there are some points to consider. Our study was not aimed to prove that 1-dose prophylaxis is as effective as a 24-hour regimen. In fact, the objectives of this study were to demonstrate how to implement a 1-dose regimen in a general hospital. The fact that 1-dose prophylaxis reduces surgical site infections as effectively as a 24-hour regimen had already been demonstrated in innumerous trials, such as the one published by Scher.1 One-dose prophylaxis is a widely approved recommendation published in several guidelines,2 some of them cited in our article.
Many hospitals have tried to implement appropriate prophylaxis programs with different success rates.3 There are . . . [Full Text of this Article]
AUTHOR INFORMATION
RELATED LETTER
Are Single-Dose Preoperative Antibiotic Regimens Really Appropriate?
Andrew H. Schmidt
Arch Surg. 2007;142(6):576-577.
EXTRACT
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ABSTRACT
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