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Reducing the Incidence of Atrial Fibrillation
John V. Conte, MD
Arch Surg. 2007;142(9):821.
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JAMA
Corticosteroids for the Prevention of Atrial Fibrillation After Cardiac Surgery: A Randomized Controlled Trial
Jari Halonen, MD; Pirjo Halonen, PhD; Otso Järvinen, MD, PhD; Panu Taskinen, MD; Tommi Auvinen, MD; Matti Tarkka, MD, PhD; Mikko Hippeläinen, MD, PhD; Tatu Juvonen, MD, PhD; Juha Hartikainen, MD, PhD; Tapio Hakala, MD, PhD
Context: Atrial fibrillation (AF) is the most common arrhythmia to occur after cardiac surgery. An exaggerated inflammatory response has been proposed to be one etiological factor.
Objective: To test whether intravenous corticosteroid administration after cardiac surgery prevents AF after cardiac surgery.
Design, Setting, and Patients: A double-blind, randomized multicenter trial (study enrollment August 2005-June 2006) in 3 university hospitals in Finland of 241 consecutive patients without prior AF or flutter and scheduled to undergo first on-pump coronary artery bypass graft (CABG) surgery, aortic valve replacement, or combined CABG surgery and aortic valve replacement.
Intervention: Patients . . . [Full Text of this Article]
AUTHOR INFORMATION
RELATED ARTICLE
Corticosteroids for the Prevention of Atrial Fibrillation After Cardiac Surgery: A Randomized Controlled Trial
Jari Halonen, Pirjo Halonen, Otso Järvinen, Panu Taskinen, Tommi Auvinen, Matti Tarkka, Mikko Hippeläinen, Tatu Juvonen, Juha Hartikainen, and Tapio Hakala
JAMA. 2007;297(14):1562-1567.
ABSTRACT
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