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Survival Analysis of Patients With Transplantable Recurrent Hepatocellular Carcinoma—Invited Critique
John J. Brems, MD
Arch Surg. 2008;143(1):74.
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| Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings. |
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Ng and colleagues have demonstrated that OLT can be safely performed for salvage in patients with recurrent HCC. The study group consisted of 60 patients who developed recurrent intrahepatic HCC after primary hepatic resection. Of the 60 patients, 12 underwent salvage OLT and 48 underwent various nontransplant therapies. These therapies included hepatic re-resection, TACE, and PEI. In comparing overall survival between the 2 treatment options, the authors found no difference between salvage transplant and nontransplant therapies for patients with recurrent HCC.
Nine of the 12 patients who underwent salvage OLT received a live donor liver. All 9 of these donors weathered the procedure well, with no major morbidity and no mortality. Therefore, salvage liver transplant for HCC may become an important indication for the use of live donor livers.
It is interesting to note that the recurrence rate of HCC after salvage OLT (41%) was substantially . . . [Full Text of this Article]
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Kelvin K. Ng, Chung Mau Lo, Chi Leung Liu, Ronnie T. P. Poon, See Ching Chan, and Sheung Tat Fan
Arch Surg. 2008;143(1):68-74.
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