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Perioperative Carcinoembryonic Antigen Measurements to Predict Curability After Liver Resection for Colorectal Metastases—Invited Critique
Anton J. Bilchik, MD, PhD
Arch Surg. 2008;143(12):1158-1159.
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Hepatic resection is the only curative option for patients with hepatic metastases from colorectal cancer (CRC). Five-year survival rates after resection have reached almost 60% in recent series.1-3 This is largely attributed to more sophisticated preoperative imaging techniques, highly sensitive intraoperative ultrasonographic detection of small metastases, improved surgical techniques, and more effective systemic therapies.3-4
Improved survival and decreased mortality for patients with hepatic CRC have changed the criteria for resection. In the past, surgical candidates were those with no more than 3 tumors, tumors less than 5 cm in greatest diameter, no bilobar disease, no extrahepatic disease, and tumors that could be removed with at least a 1-cm margin of normal hepatic parenchyma. In the modern era of hepatic surgery, the number of candidates for resection has been raised by innovative techniques to increase residual hepatic reserve (portal vein embolization, 2-stage hepatectomy, and radiofrequency ablation) . . . [Full Text of this Article]
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Perioperative Carcinoembryonic Antigen Measurements to Predict Curability After Liver Resection for Colorectal Metastases: A Prospective Study
Elie Oussoultzoglou, Edoardo Rosso, Pascal Fuchshuber, Victor Stefanescu, Bala Diop, Giorgio Giraudo, Patrick Pessaux, Philippe Bachellier, and Daniel Jaeck
Arch Surg. 2008;143(12):1150-1158.
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