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Arch Surg. 2008;143(4):422.

	Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings.

Answer: Secondary Ovarian Neoplasm

Histologic examination showed a moderately differentiated adenocarcinoma forming mucus-producing glands. The tumor cells stained positively for cytokeratins 20 and 7 and negative for estrogen receptors. The immunohistochemical profile was in keeping with metastatic colon cancer. The patient made an uneventful recovery and underwent palliative chemotherapy. Unfortunately, 18 months later her disease progressed to recurrent peritoneal disease.

Between 5% and 20% of ovarian tumors are metastatic from other malignancies.¹ Of the gastrointestinal metastases, between 30% and 65% (second only to the stomach) originate from a colorectal primary malignancy.²

Colorectal metastases present either as Krukenberg tumors¹ or as pseudo-Meigs syndrome (nonmalignant ascites or pleural effusions).³ Most are detected incidentally either during operation or preoperative imaging. The remainder present as recurrent disease. Sixty-six percent of deposits are bilateral.⁴ These tumors occur more commonly in the premenopausal patient, with 43% occurring in patients younger than 40 years.⁵ It is thought that metastatic spread occurs . . . [Full Text of this Article]

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Arch Surg. 2008;143(4):421.
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