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David A. Kooby, MD

Arch Surg. 2008;143(8):749-750.

	Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings.

I read with interest the article by Assumpcao and colleagues, assessing outcomes for patients with hepatic metastases from rectal adenocarcinoma primary tumors. Rectal adenocarcinoma is often lumped with colon cancer; however, treatment, pattern of recurrence, and outcome can be quite different. Only 24% of hepatic resections in the current study were in patients with a primary rectal tumor site, whereas the rectum represents the primary site for nearly 33% of all colorectal cancer cases. This disparity has been demonstrated¹ and may stem from the increased complexity of treating patients with rectal cancer, which makes them less suitable for combined or subsequent partial hepatectomy.

Treatment of metastatic colorectal cancer is in flux. Medical options have increased, and survival for patients with unresectable disease is better.² In some cases, a complete histological response is noted in resected specimens; however, even for those with residual disease following chemotherapy, responses . . . [Full Text of this Article]

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Patterns of Recurrence Following Liver Resection for Colorectal Metastases: Effect of Primary Rectal Tumor Site
Lia Assumpcao, Michael A. Choti, Ana Luiza Gleisner, Richard D. Schulick, Michael Swartz, Joseph Herman, Susan L. Gearhart, and Timothy M. Pawlik
Arch Surg. 2008;143(8):743-749.
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