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Perioperative Supplemental Oxygen Therapy and Surgical Site Infection—Invited Critique
Lena M. Napolitano, MD, FCCP, FCCM
Arch Surg. 2009;144(4):366-367.
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The prevention of SSIs is a goal of all surgeons. A variety of measures have been definitively identified to reduce SSIs, including perioperative antimicrobial drug prophylaxis (including proper antibiotic drug selection, dosage, timing, redosing, and discontinuation), an appropriate hair removal technique if necessary, appropriate skin preparation, maintenance of patient normothermia, and maintenance of euglycemia. These and other evidence-based recommendations were made in the 1999 Guideline for the Prevention of Surgical Site Infection.1
Despite excellent evidence supporting these interventions for SSI prevention, full compliance has not yet been achieved with implementation of these measures.2 The Surgical Infection Prevention Project,3-4 with a goal to decrease the morbidity and mortality associated with SSIs, documented that only 55.7% of Medicare patients received preoperative antibiotics for SSI prevention within 1 hour of surgical incision.5 A national collaborative (44 hospitals) that initiated these proven SSI prevention practices documented a 27% . . . [Full Text of this Article]
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Perioperative Supplemental Oxygen Therapy and Surgical Site Infection: A Meta-analysis of Randomized Controlled Trials
Motaz Qadan, Ozan Akça, Suhal S. Mahid, Carlton A. Hornung, and Hiram C. Polk, Jr
Arch Surg. 2009;144(4):359-366.
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