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Christopher L. Wolfgang, MD, PhD

Arch Surg. 2008;143(3):253.

	Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings.

Major hepatic resections are often required for the treatment of primary and secondary hepatic malignancies. A key step in planning a major hepatectomy is predicting the risk of PHLF. It is generally accepted that a postoperative liver remnant volume of 25% or greater is sufficient to minimize the risk of PHLF in a healthy liver.¹ However, this method is incapable of determining a subtle decrement in baseline hepatic function. This is a significant limitation in patients with cirrhosis or chemotherapy-induced steatohepatitis. To augment volumetric analysis, functional tests such as indocyanine green excretion are under investigation for their role as a predictor of PHLF.²

Because there is currently no effective means to bridge patients with PHLF to sufficient liver regeneration, the ideal predictor of PHLF should be a preoperative assessment. Rahman and colleagues propose the use of early postoperative serum CRP level to predict PHLF. As . . . [Full Text of this Article]

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Prognostic Utility of Postoperative C-reactive Protein for Posthepatectomy Liver Failure
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