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John Niederhuber, MD; Irving, MD; Ann Arbor

AMA Arch Surg. 1970;100(2):126-128.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

The opportunity to successfully perform permanent cutaneous homografting in the treatment of the severely burned patient is a rarity. At the present time, it necessitates the involvement of monozygotic twins. The realization of its success demonstrates the tremendous breakthrough in burn therapy which could be accomplished by the solving of the antigen-antibody problems related to homotransplantation.

The first attempts at cutaneous homografting probably occurred in the late 1880's. Girdner¹ and Schede² in 1881 are generally accepted to be the first to have reported the attempted use of fresh cadaver grafts. Since that time it has been established that successful cutaneous homografting can occur between monozygotic twins and in patients with a gammaglobulinemia. It has also been reported in extremely rare instances of chance genetic similarity.

At the present time, there have been six reported instances of a monozygotic twin serving as a source of cutaneous graft in the treatment of . . . [Full Text PDF of this Article]

Author Affiliations
From the University of Michigan Burn Center and the Department of Surgery, University of Michigan Medical Center, Ann Arbor.

Footnotes
Submitted for publication June 27, 1969.

Reprint requests to Department of Surgery, University of Michigan Medical Center, Ann Arbor (Dr. Feller).

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