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Prophylactic Closed Antibiotic-Detergent Irrigation

Dariush Kia, MD; Lester R. Dragstedt, II, MD

AMA Arch Surg. 1970;100(3):229-231.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

Wound infections continue to plague the surgeon, despite the development of antibiotics and improved aseptic technique. The development of infection in clean surgical wounds depends upon many factors, not the least being the presence of pathogenic bacteria. Probably wound infection is the result of the interaction of many local environmental factors such as the blood supply, modified by the trauma of surgery, the general condition of the patient, the contamination of the ambient air, the suture material used, and surgical skill. Since the basis of all wound infection is bacteria, infection could theoretically be eliminated if the organisms could be totally eradicated.

Systemic prophylactic antibiotics have fallen into disrepute and are used by most surgeons only in selected circumstances. In presenting this paper, the literature has been reviewed and a case is presented in order to emphasize the efficacy of topical antibiotic detergent irrigation in the prevention of wound infection . . . [Full Text PDF of this Article]

Author Affiliations
Des Moines, Iowa

From the Department of Surgery, Veterans Administration Hospital, Des Moines, Iowa.

Footnotes
Accepted for publication Nov 11, 1969.

Reprint requests to Veterans Administration Hospital, Des Moines, Iowa 50308 (Dr. Dragstedt).

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