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Osseous Metaplasia in the Human Mammary Gland
Charles J. France, MD;
Joseph P. O'Connell, MD
AMA Arch Surg. 1970;100(3):238-239.
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| Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings. |
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Although bone and cartilage have been described in a variety of extra-osseous nonneoplastic disease entities, references to such changes in the breast are rare. Willis1 details instances of bone formation in scars, skeletal muscle (myositis ossificans), arteries (atherosclerosis), cardiac valves (endocarditis), lungs (tuberculosis), lymph glands (tuberculosis), chronic salpingitis, and pancreas' (fat necrosis), as well as rare examples in skin, meninges, eye, thyroid, and the adrenal. It is significant that this study does not include any instances of involvement of the human breast. Review of the literature has failed to disclose any reported cases of ossification of the breasts related to chronic mastitis. In contrast to this, the occurrence of cartilage and bone have been described in association with both benign and malignant neoplasms of the breast.
The case described below is the first reported case of ossification of the breast associated with nonspecific chronic mastitis. It is also notable
. . . [Full Text PDF of this Article]
Author Affiliations
Detroit
From the departments of surgery (Dr. France) and pathology (Dr. O'Connell), St. John Hospital, Detroit. Dr. O'Connell is now at Suburban Hospital, Bethesda, Md.
Footnotes
Accepted for publication Nov 17, 1969.
Reprint requests to Department of Surgery, St. John Hospital, Detroit 48200 (Dr. France).
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